PATHOGNOMONIC
Signs of Disease
Classical pathognomonic signs, tested against the evidence to see which will truly earn the title.
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Pathognomonic Signs of Disease is a physician-authored medical atlas and study companion for learners who want more than "sign = disease" memorization.
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Written by Mario D. Caldararo, MD, MS.
The Book
PATHOGNOMONICSigns of Disease
A full-color visual atlas that separates true pathognomonic findings from classic-but-imperfect medical teaching pearls.
Written with the rigor of a medical encyclopedia, Pathognomonic Signs of Disease presents a curated collection of classic physical, radiographic, and microscopic findings, pairing each sign with the disease it suggests, the mechanism behind it, and whether the evidence supports its pathognomonic status — or not.
Public Writing & Social Media
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I post regularly on diagnostic reasoning, pathognomonic signs, medical history, and evidence-based mythbusting across X, Threads, Bluesky, Instagram, YouTube, Substack, and TikTok.
Attribution & Transparency
Image Credits
All Creative Commons images used in my social media posts are properly attributed. View the full credits list — including thumbnails, license information, and links to original sources.